A neuropeptide in immune-mediated inflammation, Y?
نویسندگان
چکیده
Disturbances in crosstalk between the immune system and the sympathetic nervous system (SNS) can contribute to the pathogenesis of Th1-mediated autoimmunity. Recent studies indicate that neuropeptide Y (NPY) has a major role in the regulation of Th1 responses. The precise role of NPY has been an enigma, but a recent study provides a breakthrough, demonstrating that NPY has a bimodal role as a negative regulator of T cells and an activator of antigen-presenting cell function.
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ورودعنوان ژورنال:
- Trends in immunology
دوره 27 4 شماره
صفحات -
تاریخ انتشار 2006